Póster Congreso ESHRE20: A new oral treatment based on the ATM/ATR DNA repair pathways enhancement reduce sperm DNA damage and improve semen parameters
P-068 Study question: Can double-strand sperm DNA breaks and semen parameters be improved by oral administration of antioxidants and ATM/ATR-enhancers? Summary answer: A new treatment based on ATM/ATR-repair-pathways enhancement significantly reduced double-strand sperm DNA breaks and improved semen parameters. What is known already: Double-strand breaks (DSB) take place during male meiosis to enable DNA recombination […]
Póster ESHRE 2017: Evolutionary-like selection on-a-chip: Using microfluidics to isolate the fittest sperm
Study question: To develop a microfluidic device for selective sorting of motile, morphologically normal sperm with high DNA integrity for ICSI applications. Summary answer: Microfluidic chip sorted human sperm showed higher motility, morphologically normal and DNA integrity compared to unsorted or traditionally sorted sperm. What is known already: The path that sperm take through the […]
ESHRE 2017: Selection of spermatozoa with higher chromatin integrity through a microfluidics device
Study question: We tested a simple method to enrich spermatozoa with higher progressive motility and superior chromatin status in men with normal and abnormal semen parameters. Summary answer: A microfluidics device was able to isolate spermatozoa with higher progressive motility and the lowest incidence of chromatin fragmentation in oligo- and normo-spermic semen. What is known […]
Improving pregnancy rate in IVF cycles by preparing sperm via microfluidic sperm chips
Effect of microfluidic sperm chips to sperm motility and DNA integrity improvement is already known by some studies. Although, microfluidic technologies were introduced in ART field at the beginning of 21st century and are being advanced from day to day, there is still no prevailing utilization in laboratories and there are few studies presenting their […]
