ESHRE 2018: Impact of microfluidic sperm sorting on embryo quality and comprehensive chromosome screening outcomes of couples with repeated implantation failure
What is the impact of the microfluidic sperm selection technique for IVF/ICSI on embryo quality and euploidy rates in couples with Repeated Implantation Failure (RIF)? When microfluid chip-sorted spermatozoa is used for IVF/ICSI, a higher number of top quality blastocysts and better euploidy rates were observed compared to standard selection. This was a retrospective analysis between 2016 […]
Improving pregnancy rate in IVF cycles by preparing sperm via microfluidic sperm chips
Effect of microfluidic sperm chips to sperm motility and DNA integrity improvement is already known by some studies. Although, microfluidic technologies were introduced in ART field at the beginning of 21st century and are being advanced from day to day, there is still no prevailing utilization in laboratories and there are few studies presenting their […]
Póster ESHRE 2017: Evolutionary-like selection on-a-chip: Using microfluidics to isolate the fittest sperm
Study question: To develop a microfluidic device for selective sorting of motile, morphologically normal sperm with high DNA integrity for ICSI applications. Summary answer: Microfluidic chip sorted human sperm showed higher motility, morphologically normal and DNA integrity compared to unsorted or traditionally sorted sperm. What is known already: The path that sperm take through the […]
ESHRE 2017: Selection of spermatozoa with higher chromatin integrity through a microfluidics device
Study question: We tested a simple method to enrich spermatozoa with higher progressive motility and superior chromatin status in men with normal and abnormal semen parameters. Summary answer: A microfluidics device was able to isolate spermatozoa with higher progressive motility and the lowest incidence of chromatin fragmentation in oligo- and normo-spermic semen. What is known […]
ASRM 2018: A Microfluidic Device for Selecting the Most Progressively Motile Spermatozoa Yields a Higher Rate of Euploid Embryos
Objective: We tested a novel approach for treating couples with complete and persistent embryo aneuploidy. Using a microfluidic device, we selected spermatozoa with the highest progressive motility and genomic integrity, capable of generating euploid embryos. Materials and Methods: Consenting men had their ejaculates screened by standard semen analysis according to WHO 2010 criteria. Specimens were […]
Effects of the microfluidic chip technique in sperm selection for intracytoplasmic sperm injection for unexplained infertility: a prospective, randomized controlled trial.
PURPOSE: The new-generation spermatozoon selection method, microfluidic technique called Fertile Chip® gives the chance to select spermatozoa with lower DNA fragmentation indexes. We aimed to determine the effect of microfluidic techniques for spermatozoon selection in ICSI treatment in patients with unexplained infertility.
Comparative study of fertility parameters in vitrified human spermatozoa in the presence or absence of EmbryORP ® : A novel antioxidant
Abstract The cryopreservation of spermatozoa has the main purpose of preserving male fertility. However, current preservation techniques have shown to produce lesions in the structure and alter sperm functions, probably due to the production of reactive oxygen species (ROS) during cryopreservation. To overcome the damage provoked by ROS, we introduced a novel antioxidant called EmbryORP® in […]
