New Oral Supplementation to Reduce Sperm DNA Damage and Improve Male Fertility

The study investigates a new oral supplementation based on the Ataxia-Telangiectasia-Mutated (ATM) gene repair pathway to reduce sperm DNA damage and improve semen parameters in infertile men. Three formulations were tested, including two containing curcumin and Ginkgo Biloba extract, measuring DNA damage levels and semen quality in 71 patients after 13 weeks. The formulation with […]

Póster Congreso ESHRE20: A new oral treatment based on the ATM/ATR DNA repair pathways enhancement reduce sperm DNA damage and improve semen parameters

P-068 Study question: Can double-strand sperm DNA breaks and semen parameters be improved by oral administration of antioxidants and ATM/ATR-enhancers? Summary answer: A new treatment based on ATM/ATR-repair-pathways enhancement significantly reduced double-strand sperm DNA breaks and improved semen parameters. What is known already: Double-strand breaks (DSB) take place during male meiosis to enable DNA recombination […]